Seeking new approach for therapeutic treatment of cholera disease via inhibition of bacterial carbonic anhydrases: experimental and theoretical studies for sixteen benzenesulfonamide derivatives

A series of sixteen benzenesulfonamide derivatives has been synthesised and tested as inhibitors of Vibrio cholerae carbonic anhydrase (CA) enzymes, belonging to α-CA, β-CA, and γ-CA classes (VchCAα, VchCAβ, and VchCAγ). The determined K(i) values were compared to those of selected human CA isoforms...

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Detalles Bibliográficos
Autores principales: Gitto, Rosaria, De Luca, Laura, Mancuso, Francesca, Del Prete, Sonia, Vullo, Daniela, Supuran, Claudiu T., Capasso, Clemente
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691843/
https://www.ncbi.nlm.nih.gov/pubmed/31282228
http://dx.doi.org/10.1080/14756366.2019.1618292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691843/
https://www.ncbi.nlm.nih.gov/pubmed/31282228
http://dx.doi.org/10.1080/14756366.2019.1618292

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