Identification of TMAO-producer phenotype and host–diet–gut dysbiosis by carnitine challenge test in human and germ-free mice

OBJECTIVE: The gut microbiota-derived metabolite, trimethylamine N-oxide (TMAO) plays an important role in cardiovascular disease (CVD). The fasting plasma TMAO was shown as a prognostic indicator of CVD incident in patients and raised the interest of intervention targeting gut microbiota. Here we d...

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Detalles Bibliográficos
Autores principales: Wu, Wei-Kai, Chen, Chieh-Chang, Liu, Po-Yu, Panyod, Suraphan, Liao, Ben-Yang, Chen, Pei-Chen, Kao, Hsien-Li, Kuo, Han-Chun, Kuo, Ching-Hua, Chiu, Tina H T, Chen, Rou-An, Chuang, Hsiao-Li, Huang, Yen-Te, Zou, Hsin-Bai, Hsu, Cheng-Chih, Chang, Ting-Yan, Lin, Chin-Lon, Ho, Chi-Tang, Yu, Hon-Tsen, Sheen, Lee-Yan, Wu, Ming-Shiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Gut Microbiota
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691853/
https://www.ncbi.nlm.nih.gov/pubmed/30377191
http://dx.doi.org/10.1136/gutjnl-2018-317155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691853/
https://www.ncbi.nlm.nih.gov/pubmed/30377191
http://dx.doi.org/10.1136/gutjnl-2018-317155

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