Lupus-associated atypical memory B cells are mTORC1-hyperactivated and functionally dysregulated

OBJECTIVES: A population of atypical memory B cells (AtMs) are greatly expanded in patients with active lupus, but their generation and pathophysiological roles are poorly defined. The aim of this study was to comprehensively characterise lupus AtMs with a purpose to identify therapeutic clues to ta...

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Detalles Bibliográficos
Autores principales: Wu, Chunmei, Fu, Qiong, Guo, Qiang, Chen, Sheng, Goswami, Shyamal, Sun, Shuhui, Li, Teng, Cao, Xingjian, Chu, Fuying, Chen, Zechuan, Liu, Mei, Liu, Yuanhua, Fu, Ting, Hao, Pei, Hao, Yi, Shen, Nan, Bao, Chunde, Zhang, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Systemic Lupus Erythematosus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691860/
https://www.ncbi.nlm.nih.gov/pubmed/31142473
http://dx.doi.org/10.1136/annrheumdis-2019-215039

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691860/
https://www.ncbi.nlm.nih.gov/pubmed/31142473
http://dx.doi.org/10.1136/annrheumdis-2019-215039

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