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Synergistic effects of a cremophor EL drug delivery system and its U0126 cargo in an ex vivo model

Neuroprotection has proven clinically unsuccessful in subarachnoid hemorrhage. We believe that this is because the major component in the early damage pathway, the vascular wall, has not been given the necessary focus. U0126 is a potent inhibitor of vascular phenotypical changes, exemplified by func...

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Detalles Bibliográficos
Autores principales: Christensen, S. T., Grell, A. S., Johansson, S. E., Andersson, C. M., Edvinsson, L., Haanes, K. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691891/
https://www.ncbi.nlm.nih.gov/pubmed/31274009
http://dx.doi.org/10.1080/10717544.2019.1636421