Synthesis, activity evaluation, and pro-apoptotic properties of novel 1,2,4-triazol-3-amine derivatives as potent anti-lung cancer agents

In this study, a series of 4,5-bis(substituted phenyl)-4H-1,2,4-triazol-3-amine compounds was designed, synthesised, and evaluated to determine their potential as anti-lung cancer agents. According to the results of screening of lung cancer cell lines A549, NCI-H460, and NCI-H23 in vitro, most of th...

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Detalles Bibliográficos
Autores principales: Sun, Xian-yu, Zhong, Chun-yan, Qiu, Qing-qing, Li, Zhen-wang, Liu, Mei-yu, Wang, Xin, Jin, Cheng-hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691921/
https://www.ncbi.nlm.nih.gov/pubmed/31286781
http://dx.doi.org/10.1080/14756366.2019.1636044

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691921/
https://www.ncbi.nlm.nih.gov/pubmed/31286781
http://dx.doi.org/10.1080/14756366.2019.1636044

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