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Inhibition of proliferation and migration of tumor cells through phenylboronic acid-functionalized polyamidoamine-mediated delivery of a therapeutic DNAzyme Dz13

BACKGROUND: The phenylboronic acid-functionalized polyamidoamine (PP) was employed as a gene carrier for Dz13 delivery, inducing an obvious anticancer response. MATERIALS AND METHODS: The Dz13 condensation ability of PP was evaluated through gel retardation assay. The cellular uptake mechanism of PP...

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Detalles Bibliográficos
Autores principales: Yang, Jiebing, Zhang, Jiayuan, Xing, Jiakai, Shi, Zhiyuan, Han, Haobo, Li, Quanshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6691943/
https://www.ncbi.nlm.nih.gov/pubmed/31496692
http://dx.doi.org/10.2147/IJN.S211744