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Induction of systemic, mucosal and memory antibody responses targeting Vibrio cholerae O1 O-specific polysaccharide (OSP) in adults following oral vaccination with an oral killed whole cell cholera vaccine in Bangladesh

BACKGROUND: Oral cholera vaccine (OCV) containing killed Vibrio cholerae O1 and O139 organisms (Bivalent-OCV; Biv-OCV) are playing a central role in global cholera control strategies. OCV is currently administered in a 2-dose regimen (day 0 and 14). There is a growing body of evidence that immune re...

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Detalles Bibliográficos
Autores principales: Akter, Aklima, Dash, Pinki, Aktar, Amena, Jahan, Sultana Rownok, Afrin, Sadia, Basher, Salima Raiyan, Hakim, Al, Lisa, Asura Khanam, Chowdhury, Fahima, Khan, Ashraful I., Xu, Peng, Charles, Richelle C., Kelly, Meagan, Kováč, Pavol, Harris, Jason B., Bhuiyan, Taufiqur Rahman, Calderwood, Stephen B., Ryan, Edward T., Qadri, Firdausi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692040/
https://www.ncbi.nlm.nih.gov/pubmed/31369553
http://dx.doi.org/10.1371/journal.pntd.0007634