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Altered fibrinolytic system in rat models of depression and patients with first-episode depression

Tissue plasminogen activator (tPA) is a serine protease involved in cleavage of neurotrophic factors. In addition, tPA and neuroserpin can also directly bind to low density lipoprotein receptor-related protein 1 (LRP1), promoting neurogenesis and neurite outgrowth. Given both the cleavage and non-cl...

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Detalles Bibliográficos
Autores principales: Han, Wenxiu, Dang, Ruili, Xu, Pengfei, Li, Gongying, Zhou, Xueyuan, Chen, Lei, Guo, Yujin, Yang, Mengqi, Chen, Dan, Jiang, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692056/
https://www.ncbi.nlm.nih.gov/pubmed/31417944
http://dx.doi.org/10.1016/j.ynstr.2019.100188