PHLPP1 counter-regulates STAT1-mediated inflammatory signaling

Inflammation is an essential aspect of innate immunity but also contributes to diverse human diseases. Although much is known about the kinases that control inflammatory signaling, less is known about the opposing phosphatases. Here we report that deletion of the gene encoding PH domain Leucine-rich...

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Detalles Bibliográficos
Autores principales: Cohen Katsenelson, Ksenya, Stender, Joshua D, Kawashima, Agnieszka T, Lordén, Gema, Uchiyama, Satoshi, Nizet, Victor, Glass, Christopher K, Newton, Alexandra C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692130/
https://www.ncbi.nlm.nih.gov/pubmed/31408005
http://dx.doi.org/10.7554/eLife.48609

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692130/
https://www.ncbi.nlm.nih.gov/pubmed/31408005
http://dx.doi.org/10.7554/eLife.48609

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