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The HCN Channel Voltage Sensor Undergoes A Large Downward Motion During Hyperpolarization
Voltage-gated ion channels (VGICs) contain positively-charged residues within the S4 helix of the voltage-sensing domain (VSD) that are displaced in response to changes in transmembrane voltage, promoting conformational changes that open the pore. Pacemaker HCN channels are unique among VGICs becaus...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692172/ https://www.ncbi.nlm.nih.gov/pubmed/31285608 http://dx.doi.org/10.1038/s41594-019-0259-1 |