Nuclear and cytoplasmic WDR-23 isoforms mediate differential effects on GEN-1 and SKN-1 substrates

Maintaining a healthy cellular environment requires the constant control of proteostasis. E3 ubiquitin ligase complexes facilitate the post-translational addition of ubiquitin, which based on the quantity and specific lysine linkages, results in different outcomes. Our studies reveal the CUL4-DDB1 s...

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Detalles Bibliográficos
Autores principales: Spatola, Brett N., Lo, Jacqueline Y., Wang, Bin, Curran, Sean P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692315/
https://www.ncbi.nlm.nih.gov/pubmed/31409866
http://dx.doi.org/10.1038/s41598-019-48286-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692315/
https://www.ncbi.nlm.nih.gov/pubmed/31409866
http://dx.doi.org/10.1038/s41598-019-48286-y

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