MCT1 relieves osimertinib-induced CRC suppression by promoting autophagy through the LKB1/AMPK signaling

Colorectal cancer (CRC) is one of the most frequently diagnosed cancers worldwide. Development of novel chemotherapeutics is still required to enable successful treatment and improve survival for CRC patients. Here, we found that osimertinib (OSI) exhibits potent anti-CRC effects by inducing apoptos...

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Detalles Bibliográficos
Autores principales: Jin, Ping, Jiang, Jingwen, Xie, Na, Zhou, Li, Huang, Zhao, Zhang, Lu, Qin, Siyuan, Fu, Shuyue, Peng, Liyuan, Gao, Wei, Li, Bowen, Lei, Yunlong, Nice, Edouard C., Li, Changlong, Shao, Jichun, Xie, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692318/
https://www.ncbi.nlm.nih.gov/pubmed/31409796
http://dx.doi.org/10.1038/s41419-019-1844-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692318/
https://www.ncbi.nlm.nih.gov/pubmed/31409796
http://dx.doi.org/10.1038/s41419-019-1844-2

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