mTOR direct crosstalk with STAT5 promotes de novo lipid synthesis and induces hepatocellular carcinoma

Hepatocellular carcinoma (HCC) can be the last step of nonalcoholic fatty liver disease (NAFLD) evolution, and the main characteristic of NAFLD is alteration in lipid metabolism. However, the mechanisms of abnormal lipid metabolism in NAFLD and HCC progression are yet to be identified. Here, we demo...

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Detalles Bibliográficos
Autores principales: Li, Ting, Weng, Jun, Zhang, Yue, Liang, Kangyan, Fu, Gongbo, Li, Yang, Bai, Xiaochun, Gao, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692326/
https://www.ncbi.nlm.nih.gov/pubmed/31409773
http://dx.doi.org/10.1038/s41419-019-1828-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692326/
https://www.ncbi.nlm.nih.gov/pubmed/31409773
http://dx.doi.org/10.1038/s41419-019-1828-2

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