Ferritin nanovehicle for targeted delivery of cytochrome C to cancer cells

In this work, we have exploited the unique properties of a chimeric archaeal-human ferritin to encapsulate, deliver and release cytochrome c and induce apoptosis in a myeloid leukemia cell line. The chimeric protein combines the versatility in 24-meric assembly and cargo incorporation capability of...

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Detalles Bibliográficos
Autores principales: Macone, Alberto, Masciarelli, Silvia, Palombarini, Federica, Quaglio, Deborah, Boffi, Alberto, Trabuco, Matilde Cardoso, Baiocco, Paola, Fazi, Francesco, Bonamore, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692331/
https://www.ncbi.nlm.nih.gov/pubmed/31409839
http://dx.doi.org/10.1038/s41598-019-48037-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692331/
https://www.ncbi.nlm.nih.gov/pubmed/31409839
http://dx.doi.org/10.1038/s41598-019-48037-z

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