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Ferritin nanovehicle for targeted delivery of cytochrome C to cancer cells
In this work, we have exploited the unique properties of a chimeric archaeal-human ferritin to encapsulate, deliver and release cytochrome c and induce apoptosis in a myeloid leukemia cell line. The chimeric protein combines the versatility in 24-meric assembly and cargo incorporation capability of...
Autores principales: | Macone, Alberto, Masciarelli, Silvia, Palombarini, Federica, Quaglio, Deborah, Boffi, Alberto, Trabuco, Matilde Cardoso, Baiocco, Paola, Fazi, Francesco, Bonamore, Alessandra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692331/ https://www.ncbi.nlm.nih.gov/pubmed/31409839 http://dx.doi.org/10.1038/s41598-019-48037-z |
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