Horse immunization with short-chain consensus α-neurotoxin generates antibodies against broad spectrum of elapid venomous species

Antivenoms are fundamental in the therapy for snakebites. In elapid venoms, there are toxins, e.g. short-chain α-neurotoxins, which are quite abundant, highly toxic, and consequently play a major role in envenomation processes. The core problem is that such α-neurotoxins are weakly immunogenic, and...

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Detalles Bibliográficos
Autores principales: de la Rosa, Guillermo, Olvera, Felipe, Archundia, Irving G., Lomonte, Bruno, Alagón, Alejandro, Corzo, Gerardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692343/
https://www.ncbi.nlm.nih.gov/pubmed/31409779
http://dx.doi.org/10.1038/s41467-019-11639-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692343/
https://www.ncbi.nlm.nih.gov/pubmed/31409779
http://dx.doi.org/10.1038/s41467-019-11639-2

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