A VNTR Regulates miR-137 Expression Through Novel Alternative Splicing and Contributes to Risk for Schizophrenia

The MIR137HG gene encoding microRNA-137 (miR-137) is genome-wide associated with schizophrenia (SZ), however, the underlying molecular mechanisms remain unknown. Through cloning and sequencing of individual transcripts from fetal and adult human brain tissues we describe novel pri-miR-137 splice var...

Descripción completa

Detalles Bibliográficos
Autores principales: Pacheco, Ashley, Berger, Ralph, Freedman, Robert, Law, Amanda J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692358/
https://www.ncbi.nlm.nih.gov/pubmed/31409837
http://dx.doi.org/10.1038/s41598-019-48141-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692358/
https://www.ncbi.nlm.nih.gov/pubmed/31409837
http://dx.doi.org/10.1038/s41598-019-48141-0

Ejemplares similares