Smu1 and RED are required for activation of spliceosomal B complexes assembled on short introns

Human pre-catalytic spliceosomes contain several proteins that associate transiently just prior to spliceosome activation and are absent in yeast, suggesting that this critical step is more complex in higher eukaryotes. We demonstrate via RNAi coupled with RNA-Seq that two of these human-specific pr...

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Detalles Bibliográficos
Autores principales: Keiper, Sandra, Papasaikas, Panagiotis, Will, Cindy L., Valcárcel, Juan, Girard, Cyrille, Lührmann, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692369/
https://www.ncbi.nlm.nih.gov/pubmed/31409787
http://dx.doi.org/10.1038/s41467-019-11293-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692369/
https://www.ncbi.nlm.nih.gov/pubmed/31409787
http://dx.doi.org/10.1038/s41467-019-11293-8

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