MRTF-A controls myofibroblastic differentiation of human multipotent stromal cells and their tumour-supporting function in xenograft models

Tumour growth and metastatic colonization is strongly influenced by the tumour stroma, including cancer-associated fibroblasts (CAF). Multipotent mesenchymal stromal cells (MSC) are a possible source of CAF following myofibroblastic differentiation, and we have previously shown that MSC support tumo...

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Detalles Bibliográficos
Autores principales: Werner, Sara, Lützkendorf, Jana, Müller, Thomas, Müller, Lutz P., Posern, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692381/
https://www.ncbi.nlm.nih.gov/pubmed/31409840
http://dx.doi.org/10.1038/s41598-019-48142-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692381/
https://www.ncbi.nlm.nih.gov/pubmed/31409840
http://dx.doi.org/10.1038/s41598-019-48142-z

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