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Establishment of serine protease htrA mutants in Helicobacter pylori is associated with secA mutations

Helicobacter pylori plays an essential role in the pathogenesis of gastritis, peptic ulcer disease, and gastric cancer. The serine protease HtrA, an important secreted virulence factor, disrupts the gastric epithelium, which enables H. pylori to transmigrate across the epithelium and inject the onco...

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Detalles Bibliográficos
Autores principales: Zawilak-Pawlik, Anna, Zarzecka, Urszula, Żyła-Uklejewicz, Dorota, Lach, Jakub, Strapagiel, Dominik, Tegtmeyer, Nicole, Böhm, Manja, Backert, Steffen, Skorko-Glonek, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692382/
https://www.ncbi.nlm.nih.gov/pubmed/31409845
http://dx.doi.org/10.1038/s41598-019-48030-6