Cargando…

Establishment of serine protease htrA mutants in Helicobacter pylori is associated with secA mutations

Helicobacter pylori plays an essential role in the pathogenesis of gastritis, peptic ulcer disease, and gastric cancer. The serine protease HtrA, an important secreted virulence factor, disrupts the gastric epithelium, which enables H. pylori to transmigrate across the epithelium and inject the onco...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zawilak-Pawlik, Anna, Zarzecka, Urszula, Żyła-Uklejewicz, Dorota, Lach, Jakub, Strapagiel, Dominik, Tegtmeyer, Nicole, Böhm, Manja, Backert, Steffen, Skorko-Glonek, Joanna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692382/ https://www.ncbi.nlm.nih.gov/pubmed/31409845 http://dx.doi.org/10.1038/s41598-019-48030-6

Ejemplares similares

Chaperone activity of serine protease HtrA of Helicobacter pylori as a crucial survival factor under stress conditions
por: Zarzecka, Urszula, et al.
Publicado: (2019)

Functional analysis and cryo-electron microscopy of Campylobacter jejuni serine protease HtrA
por: Zarzecka, Urszula, et al.
Publicado: (2020)

Amino-Terminal Processing of Helicobacter pylori Serine Protease HtrA: Role in Oligomerization and Activity Regulation
por: Albrecht, Nicole, et al.
Publicado: (2018)

Properties of the HtrA Protease From Bacterium Helicobacter pylori Whose Activity Is Indispensable for Growth Under Stress Conditions
por: Zarzecka, Urszula, et al.
Publicado: (2019)

E-Cadherin Orthologues as Substrates for the Serine Protease High Temperature Requirement A (HtrA)
por: Bernegger, Sabine, et al.
Publicado: (2022)

Campylobacter jejuni enters gut epithelial cells and impairs intestinal barrier function through cleavage of occludin by serine protease HtrA
por: Harrer, Aileen, et al.
Publicado: (2019)

Trimer stability of Helicobacter pylori HtrA is regulated by a natural mutation in the protease domain
por: Zarzecka, Urszula, et al.
Publicado: (2023)

Function of Serine Protease HtrA in the Lifecycle of the Foodborne Pathogen Campylobacter jejuni
por: Boehm, Manja, et al.
Publicado: (2018)

Overexpression of serine protease HtrA enhances disruption of adherens junctions, paracellular transmigration and type IV secretion of CagA by Helicobacter pylori
por: Harrer, Aileen, et al.
Publicado: (2017)

Campylobacter jejuni Serine Protease HtrA Cleaves the Tight Junction Component Claudin-8
por: Sharafutdinov, Irshad, et al.
Publicado: (2020)

Campylobacter jejuni Serine Protease HtrA Induces Paracellular Transmigration of Microbiota across Polarized Intestinal Epithelial Cells
por: Sharafutdinov, Irshad, et al.
Publicado: (2022)

Analysis of the Link between the Redox State and Enzymatic Activity of the HtrA (DegP) Protein from Escherichia coli
por: Koper, Tomasz, et al.
Publicado: (2015)

The role of serine protease HtrA in acute ulcerative enterocolitis and extra-intestinal immune responses during Campylobacter jejuni infection of gnotobiotic IL-10 deficient mice
por: Heimesaat, Markus M., et al.
Publicado: (2014)

Quantification of serine protease HtrA molecules secreted by the foodborne pathogen Campylobacter jejuni
por: Neddermann, Matthias, et al.
Publicado: (2019)

Structural and Functional Analysis of Human HtrA3 Protease and Its Subdomains
por: Glaza, Przemyslaw, et al.
Publicado: (2015)

The impact of serine protease HtrA in apoptosis, intestinal immune responses and extra-intestinal histopathology during Campylobacter jejuni infection of infant mice
por: Heimesaat, Markus M, et al.
Publicado: (2014)

Bacterial serine protease HtrA as a promising new target for antimicrobial therapy?
por: Wessler, Silja, et al.
Publicado: (2017)

Temperature-induced changes of HtrA2(Omi) protease activity and structure
por: Zurawa-Janicka, Dorota, et al.
Publicado: (2012)

Identification of E-cadherin signature motifs functioning as cleavage sites for Helicobacter pylori HtrA
por: Schmidt, Thomas P., et al.
Publicado: (2016)

Characterisation of worldwide Helicobacter pylori strains reveals genetic conservation and essentiality of serine protease HtrA
por: Tegtmeyer, Nicole, et al.
Publicado: (2015)

Dynamic Distribution of the SecA and SecY Translocase Subunits and Septal Localization of the HtrA Surface Chaperone/Protease during Streptococcus pneumoniae D39 Cell Division
por: Tsui, Ho-Ching Tiffany, et al.
Publicado: (2011)

Unraveling the Dichotomy of Enigmatic Serine Protease HtrA2
por: Chakraborty, Ayon, et al.
Publicado: (2022)

Peptide lineup against Gram-negative bacterial infection – first-in-class peptide inhibitor of H. pylori HtrA
por: Perna, Anna M, et al.
Publicado: (2014)

Rapid paracellular transmigration of Campylobacter jejuni across polarized epithelial cells without affecting TER: role of proteolytic-active HtrA cleaving E-cadherin but not fibronectin
por: Boehm, Manja, et al.
Publicado: (2012)

Activity-Modulating Monoclonal Antibodies to the Human Serine Protease HtrA3 Provide Novel Insights into Regulating HtrA Proteolytic Activities
por: Singh, Harmeet, et al.
Publicado: (2014)

Protoporphyrins Enhance Oligomerization and Enzymatic Activity of HtrA1 Serine Protease
por: Jo, Hakryul, et al.
Publicado: (2014)

Molecular motion regulates the activity of the Mitochondrial Serine Protease HtrA2
por: Merski, Matthew, et al.
Publicado: (2017)

The function of bacterial HtrA is evolutionally conserved in mammalian HtrA2/Omi
por: Chung, Hea-Jong, et al.
Publicado: (2020)

The Structure of Clostridioides difficile SecA2 ATPase Exposes Regions Responsible for Differential Target Recognition of the SecA1 and SecA2-Dependent Systems
por: Lindič, Nataša, et al.
Publicado: (2020)

In Vitro Interaction of the Housekeeping SecA1 with the Accessory SecA2 Protein of Mycobacterium tuberculosis
por: Prabudiansyah, Irfan, et al.
Publicado: (2015)

SecA, a remarkable nanomachine
por: Kusters, Ilja, et al.
Publicado: (2011)

Analysis of SecA Dimerization in Solution
por: Wowor, Andy J., et al.
Publicado: (2014)

SecA Localization and SecA-Dependent Secretion Occurs at New Division Septa in Group B Streptococcus
por: Brega, Sara, et al.
Publicado: (2013)

Putative Cooperative ATP–DnaA Binding to Double-Stranded DnaA Box and Single-Stranded DnaA-Trio Motif upon Helicobacter pylori Replication Initiation Complex Assembly
por: Jaworski, Pawel, et al.
Publicado: (2021)

Assessing the Contribution of an HtrA Family Serine Protease During Borrelia turicatae Mammalian Infection
por: Jackson-Litteken, Clay D., et al.
Publicado: (2019)

SecA—a New Twist in the Tale
por: Collinson, Ian
Publicado: (2016)

HP1021 is a redox switch protein identified in Helicobacter pylori
por: Szczepanowski, Piotr, et al.
Publicado: (2021)

Protease Activity of Campylobacter jejuni HtrA Modulates Distinct Intestinal and Systemic Immune Responses in Infected Secondary Abiotic IL-10 Deficient Mice
por: Schmidt, Anna-Maria, et al.
Publicado: (2019)

The Wilms' Tumor Suppressor Protein WT1 Is Processed by the Serine Protease HtrA2/Omi
por: Hartkamp, Jörg, et al.
Publicado: (2010)

Chlamydia Serine Protease Inhibitor, targeting HtrA, as a New Treatment for Koala Chlamydia infection
por: Lawrence, Amba, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_rb8mto9jsjtig4tu2a7kfmfsbd