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RORα suppresses interleukin-6-mediated hepatic acute phase response

Acute liver failure (ALF) is characterized by loss of liver function in response to sustained augmentation of the acute-phase response (APR) in the liver, which can progress even to death. Although the inflammatory interleukin-6 (IL-6)–axis is a crucial factor that drives the hepatic APR by releasin...

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Detalles Bibliográficos
Autores principales: Kim, Ju-Yeon, Han, Yong-Hyun, Nam, Min-Woo, Kim, Hyeon-Ji, Lee, Mi-Ock
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692401/
https://www.ncbi.nlm.nih.gov/pubmed/31409825
http://dx.doi.org/10.1038/s41598-019-48171-8