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Sinus node-like pacemaker mechanisms regulate ectopic pacemaker activity in the adult rat atrioventricular ring

In adult mammalian hearts, atrioventricular rings (AVRs) surround the atrial orifices of atrioventricular valves and are hotbed of ectopic activity in patients with focal atrial tachycardia. Experimental data offering mechanistic insights into initiation and maintenance of ectopic foci is lacking. W...

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Detalles Bibliográficos
Autores principales: Logantha, Sunil Jit R. J., Kharche, Sanjay R., Zhang, Yu, Atkinson, Andrew J., Hao, Guoliang, Boyett, Mark R., Dobrzynski, Halina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692414/
https://www.ncbi.nlm.nih.gov/pubmed/31409881
http://dx.doi.org/10.1038/s41598-019-48276-0