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Molecular Mechanisms Responsible for the Rescue Effects of Pamidronate on Muscle Atrophy in Pediatric Burn Patients

Not only has pamidronate been shown to prevent inflammation associated bone resorption following burn injury, it also reduces protein breakdown in muscle. The aim of this study was to identify the molecular mechanisms responsible for muscle mass rescue in pamidronate treated compared to placebo/stan...

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Detalles Bibliográficos
Autores principales: Pin, Fabrizio, Bonetto, Andrea, Bonewald, Lynda F., Klein, Gordon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692456/
https://www.ncbi.nlm.nih.gov/pubmed/31447786
http://dx.doi.org/10.3389/fendo.2019.00543