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Cytotoxic Granule Exocytosis From Human Cytotoxic T Lymphocytes Is Mediated by VAMP7

Cytotoxic T lymphocytes kill infected or malignant cells through the directed release of cytotoxic substances at the site of target cell contact, the immunological synapse. While genetic association studies of genes predisposing to early-onset life-threatening hemophagocytic lymphohistiocytosis has...

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Detalles Bibliográficos
Autores principales: Chitirala, Praneeth, Ravichandran, Keerthana, Galgano, Donatella, Sleiman, Marwa, Krause, Elmar, Bryceson, Yenan T., Rettig, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692471/
https://www.ncbi.nlm.nih.gov/pubmed/31447853
http://dx.doi.org/10.3389/fimmu.2019.01855