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Cytotoxic Granule Exocytosis From Human Cytotoxic T Lymphocytes Is Mediated by VAMP7
Cytotoxic T lymphocytes kill infected or malignant cells through the directed release of cytotoxic substances at the site of target cell contact, the immunological synapse. While genetic association studies of genes predisposing to early-onset life-threatening hemophagocytic lymphohistiocytosis has...
Autores principales: | Chitirala, Praneeth, Ravichandran, Keerthana, Galgano, Donatella, Sleiman, Marwa, Krause, Elmar, Bryceson, Yenan T., Rettig, Jens |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692471/ https://www.ncbi.nlm.nih.gov/pubmed/31447853 http://dx.doi.org/10.3389/fimmu.2019.01855 |
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