Ambroxol Hydrochloride Improves Motor Functions and Extends Survival in a Mouse Model of Familial Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a multifactorial and fatal neurodegenerative disease. Growing evidence connects sphingolipid metabolism to the pathophysiology of ALS. In particular, levels of ceramides, glucosylceramides, and gangliosides are dysregulated in the central nervous system and at...

Descripción completa

Detalles Bibliográficos
Autores principales: Bouscary, Alexandra, Quessada, Cyril, Mosbach, Althéa, Callizot, Noëlle, Spedding, Michael, Loeffler, Jean-Philippe, Henriques, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692493/
https://www.ncbi.nlm.nih.gov/pubmed/31447678
http://dx.doi.org/10.3389/fphar.2019.00883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692493/
https://www.ncbi.nlm.nih.gov/pubmed/31447678
http://dx.doi.org/10.3389/fphar.2019.00883

Ejemplares similares