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The Hippo network kinase STK38 contributes to protein homeostasis by inhibiting BAG3-mediated autophagy

Chaperone-assisted selective autophagy (CASA) initiated by the cochaperone Bcl2-associated athanogene 3 (BAG3) represents an important mechanism for the disposal of misfolded and damaged proteins in mammalian cells. Under mechanical stress, the cochaperone cooperates with the small heat shock protei...

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Detalles Bibliográficos
Autores principales: Klimek, Christina, Jahnke, Ricarda, Wördehoff, Judith, Kathage, Barbara, Stadel, Daniela, Behrends, Christian, Hergovich, Alexander, Höhfeld, Jörg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692498/
https://www.ncbi.nlm.nih.gov/pubmed/31326538
http://dx.doi.org/10.1016/j.bbamcr.2019.07.007