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Identification of the Cell-Surface Protease ADAM9 as an Entry Factor for Encephalomyocarditis Virus

Encephalomyocarditis virus (EMCV) is an animal pathogen and an important model organism, whose receptor requirements are poorly understood. Here, we employed a genome-wide haploid genetic screen to identify novel EMCV host factors. In addition to the previously described picornavirus receptors siali...

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Detalles Bibliográficos
Autores principales: Baggen, Jim, Thibaut, Hendrik Jan, Hurdiss, Daniel L., Wahedi, Maryam, Marceau, Caleb D., van Vliet, Arno L. W., Carette, Jan E., van Kuppeveld, Frank J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692517/
https://www.ncbi.nlm.nih.gov/pubmed/31409686
http://dx.doi.org/10.1128/mBio.01780-19