The Loss of SMAD4/DPC4 Expression Associated with a Strongly Activated Hedgehog Signaling Pathway Predicts Poor Prognosis in Resected Pancreatic Cancer

Background: Pancreatic ductal adenocarcinoma (PDAC) progression is mediated by mutations in driver genes and a complex stroma that is mainly dependent on the Sonic hedgehog (Shh) signaling pathway. However, the association between driver genes and Shh-pathway proteins and their potential prognostic...

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Detalles Bibliográficos
Autores principales: Xu, Jin-Zhi, Wang, Wen-Quan, Zhang, Wu-Hu, Xu, Hua-Xiang, Gao, He-Li, Zhang, Shi-Rong, Wu, Chun-Tao, Li, Shuo, Li, Hao, Xu, Jin, Yu, Xian-Jun, Liu, Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692626/
https://www.ncbi.nlm.nih.gov/pubmed/31417657
http://dx.doi.org/10.7150/jca.30883

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692626/
https://www.ncbi.nlm.nih.gov/pubmed/31417657
http://dx.doi.org/10.7150/jca.30883

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