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Cardiovascular Adverse Events Associated With BRAF and MEK Inhibitors: A Systematic Review and Meta-analysis

IMPORTANCE: Cardiovascular adverse events (CVAEs) after treatment with BRAF and MEK inhibitors in patients with melanoma remain incompletely characterized. OBJECTIVE: To determine the association of BRAF and MEK inhibitor treatment with CVAEs in patients with melanoma compared with BRAF inhibitor mo...

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Detalles Bibliográficos
Autores principales: Mincu, Raluca I., Mahabadi, Amir A., Michel, Lars, Mrotzek, Simone M., Schadendorf, Dirk, Rassaf, Tienush, Totzeck, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692687/
https://www.ncbi.nlm.nih.gov/pubmed/31397860
http://dx.doi.org/10.1001/jamanetworkopen.2019.8890