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Lactate Induces Pro-tumor Reprogramming in Intratumoral Plasmacytoid Dendritic Cells
Plasmacytoid dendritic cells are the most efficient producers of type I interferons, viz. IFNα, in the body and thus have the ability to influence anti-tumor immune responses. But repression of effective intra-tumoral pDC activation is a key immuno-evasion strategy exhibited in tumors—tumor-recruite...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692712/ https://www.ncbi.nlm.nih.gov/pubmed/31440253 http://dx.doi.org/10.3389/fimmu.2019.01878 |