Lactate Induces Pro-tumor Reprogramming in Intratumoral Plasmacytoid Dendritic Cells

Plasmacytoid dendritic cells are the most efficient producers of type I interferons, viz. IFNα, in the body and thus have the ability to influence anti-tumor immune responses. But repression of effective intra-tumoral pDC activation is a key immuno-evasion strategy exhibited in tumors—tumor-recruite...

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Detalles Bibliográficos
Autores principales: Raychaudhuri, Deblina, Bhattacharya, Roopkatha, Sinha, Bishnu Prasad, Liu, Chinky Shiu Chen, Ghosh, Amrit Raj, Rahaman, Oindrila, Bandopadhyay, Purbita, Sarif, Jafar, D'Rozario, Ranit, Paul, Santu, Das, Anirban, Sarkar, Diptendra K., Chattopadhyay, Samit, Ganguly, Dipyaman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692712/
https://www.ncbi.nlm.nih.gov/pubmed/31440253
http://dx.doi.org/10.3389/fimmu.2019.01878

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