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Multi-omics Characterization of Interaction-mediated Control of Human Protein Abundance levels

Proteogenomic studies of cancer samples have shown that copy-number variation can be attenuated at the protein level for a large fraction of the proteome, likely due to the degradation of unassembled protein complex subunits. Such interaction-mediated control of protein abundance remains poorly char...

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Detalles Bibliográficos
Autores principales: Sousa, Abel, Gonçalves, Emanuel, Mirauta, Bogdan, Ochoa, David, Stegle, Oliver, Beltrao, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Biochemistry and Molecular Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692786/
https://www.ncbi.nlm.nih.gov/pubmed/31239291
http://dx.doi.org/10.1074/mcp.RA118.001280