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Redox-Sensitive Gelatin/Silica-Aptamer Nanogels for Targeted siRNA Delivery

RNA interference (RNAi) has potential advantages over other gene therapy approaches due to its high specificity and the ability to inhibit target gene expression. However, the stability and tissue-specific delivery of siRNA remain as the biggest obstacles for RNAi therapeutics. Here, we developed su...

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Detalles Bibliográficos
Autores principales: Zhao, Xueqin, Xi, Yinyin, Zhang, Yongming, Wu, Qiuyan, Meng, Ruiyuan, Zheng, Bin, Rei, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692808/
https://www.ncbi.nlm.nih.gov/pubmed/31414279
http://dx.doi.org/10.1186/s11671-019-3101-0