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Prolonged Prepregnant Maternal High-Fat Feeding Reduces Fetal and Neonatal Blood Glucose Concentrations by Enhancing Fetal β-Cell Development in C57BL/6 Mice

The main objective of this study was to investigate the effect of maternal obesity on offspring’s glucose metabolism during the perinatal period. Maternal obesity was established by feeding C57BL/6 mice with a high-fat (HF) diet before or during pregnancy. Our results showed that prolonged prepregna...

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Detalles Bibliográficos
Autores principales: Qiao, Liping, Wattez, Jean-Sebastien, Lim, Lauren, Rozance, Paul J., Hay, William W., Shao, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692812/
https://www.ncbi.nlm.nih.gov/pubmed/31127056
http://dx.doi.org/10.2337/db18-1308