Iatrogenic Hyperinsulinemia, Not Hyperglycemia, Drives Insulin Resistance in Type 1 Diabetes as Revealed by Comparison With GCK-MODY (MODY2)

Although insulin resistance consistently occurs with type 1 diabetes, its predominant driver is uncertain. We therefore determined the relative contributions of hyperglycemia and iatrogenic hyperinsulinemia to insulin resistance using hyperinsulinemic-euglycemic clamps in three participant groups (n...

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Detalles Bibliográficos
Autores principales: Gregory, Justin M., Smith, T. Jordan, Slaughter, James C., Mason, Holly R., Hughey, Curtis C., Smith, Marta S., Kandasamy, Balamurugan, Greeley, Siri Atma W., Philipson, Louis H., Naylor, Rochelle N., Letourneau, Lisa R., Abumrad, Naji N., Cherrington, Alan D., Moore, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2019
Materias:
Metabolism
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692813/
https://www.ncbi.nlm.nih.gov/pubmed/31092478
http://dx.doi.org/10.2337/db19-0324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692813/
https://www.ncbi.nlm.nih.gov/pubmed/31092478
http://dx.doi.org/10.2337/db19-0324

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