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Steroid receptor coactivator 3 inhibits hepatitis B virus gene expression through activating Akt signaling to prevent HNF4α nuclear translocation

BACKGROUND: Chronic hepatitis B virus (HBV) infection is one of the most serious global public health problems. The role of steroid receptor coactivator 3 (SRC-3) in HBV biosynthesis is unknown. The aim of this study is to investigate the function of SRC-3 in regulating HBV biosynthesis both in vitr...

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Detalles Bibliográficos
Autores principales: Li, Ming, Wang, Yi, Xia, Xiaochun, Mo, Pingli, Xu, Jianming, Yu, Chundong, Li, Wengang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692928/
https://www.ncbi.nlm.nih.gov/pubmed/31417670
http://dx.doi.org/10.1186/s13578-019-0328-5