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Serologic responses to the PfEMP1 DBL-CIDR head structure may be a better indicator of malaria exposure than those to the DBL-α tag

BACKGROUND: Plasmodium falciparum erythrocyte membrane protein-1 (PfEMP1) antigens play a critical role in host immune evasion. Serologic responses to these antigens have been associated with protection from clinical malaria, suggesting that antibodies to PfEMP1 antigens may contribute to natural im...

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Detalles Bibliográficos
Autores principales: Stucke, Emily M., Niangaly, Amadou, Berry, Andrea A., Bailey, Jason A., Coulibaly, Drissa, Ouattara, Amed, Lyke, Kirsten E., Laurens, Matthew B., Dara, Antoine, Adams, Matthew, Pablo, Jozelyn, Jasinskas, Algis, Nakajima, Rie, Zhou, Albert E., Agrawal, Sonia, Friedman-Klabanoff, DeAnna J., Takala-Harrison, Shannon, Kouriba, Bourema, Kone, Abdoulaye K., Rowe, J. Alexandra, Doumbo, Ogobara K., Felgner, Philip L., Thera, Mahamadou A., Plowe, Christopher V., Travassos, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692945/
https://www.ncbi.nlm.nih.gov/pubmed/31409360
http://dx.doi.org/10.1186/s12936-019-2905-9