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Serologic responses to the PfEMP1 DBL-CIDR head structure may be a better indicator of malaria exposure than those to the DBL-α tag
BACKGROUND: Plasmodium falciparum erythrocyte membrane protein-1 (PfEMP1) antigens play a critical role in host immune evasion. Serologic responses to these antigens have been associated with protection from clinical malaria, suggesting that antibodies to PfEMP1 antigens may contribute to natural im...
Autores principales: | Stucke, Emily M., Niangaly, Amadou, Berry, Andrea A., Bailey, Jason A., Coulibaly, Drissa, Ouattara, Amed, Lyke, Kirsten E., Laurens, Matthew B., Dara, Antoine, Adams, Matthew, Pablo, Jozelyn, Jasinskas, Algis, Nakajima, Rie, Zhou, Albert E., Agrawal, Sonia, Friedman-Klabanoff, DeAnna J., Takala-Harrison, Shannon, Kouriba, Bourema, Kone, Abdoulaye K., Rowe, J. Alexandra, Doumbo, Ogobara K., Felgner, Philip L., Thera, Mahamadou A., Plowe, Christopher V., Travassos, Mark A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6692945/ https://www.ncbi.nlm.nih.gov/pubmed/31409360 http://dx.doi.org/10.1186/s12936-019-2905-9 |
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