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Clinical significance of atypical protein kinase C (PKCι and PKCζ) and its relationship with yes-associated protein in lung adenocarcinoma

BACKGROUND: Protein kinase C iota (PKCι) and protein kinase C zeta (PKCζ) are two atypical protein kinase (aPKC) enzymes that contribute to cell proliferation and cancer development. The Hippo/YAP pathway is commonly disrupted and upregulated in cancers. Herein, the expression patterns and clinical...

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Detalles Bibliográficos
Autores principales: Kim, Kyung-Hee, Chung, Chaeuk, Kim, Jin-Man, Lee, Dahye, Cho, Sang Yeon, Lee, Tae Hee, Cho, Hyun Jin, Yeo, Min-Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693135/
https://www.ncbi.nlm.nih.gov/pubmed/31412817
http://dx.doi.org/10.1186/s12885-019-5992-7