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CD27- IgD- B cell memory subset associates with inflammation and frailty in elderly individuals but only in males

BACKGROUND: Immunosenescence, i.e. the aging-associated decline of the capacity of the immune system, is characterized by several distinct changes in the number and functions of the immune cells. In the case of B cells, the total number of CD19+ B cells is lower in the blood of elderly individuals t...

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Detalles Bibliográficos
Autores principales: Nevalainen, Tapio, Autio, Arttu, Kummola, Laura, Salomaa, Tanja, Junttila, Ilkka, Jylhä, Marja, Hurme, Mikko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693136/
https://www.ncbi.nlm.nih.gov/pubmed/31423147
http://dx.doi.org/10.1186/s12979-019-0159-6