Screening for genes that accelerate the epigenetic aging clock in humans reveals a role for the H3K36 methyltransferase NSD1

BACKGROUND: Epigenetic clocks are mathematical models that predict the biological age of an individual using DNA methylation data and have emerged in the last few years as the most accurate biomarkers of the aging process. However, little is known about the molecular mechanisms that control the rate...

Descripción completa

Detalles Bibliográficos
Autores principales: Martin-Herranz, Daniel E., Aref-Eshghi, Erfan, Bonder, Marc Jan, Stubbs, Thomas M., Choufani, Sanaa, Weksberg, Rosanna, Stegle, Oliver, Sadikovic, Bekim, Reik, Wolf, Thornton, Janet M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693144/
https://www.ncbi.nlm.nih.gov/pubmed/31409373
http://dx.doi.org/10.1186/s13059-019-1753-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693144/
https://www.ncbi.nlm.nih.gov/pubmed/31409373
http://dx.doi.org/10.1186/s13059-019-1753-9

Ejemplares similares