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scAlign: a tool for alignment, integration, and rare cell identification from scRNA-seq data

scRNA-seq dataset integration occurs in different contexts, such as the identification of cell type-specific differences in gene expression across conditions or species, or batch effect correction. We present scAlign, an unsupervised deep learning method for data integration that can incorporate par...

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Detalles Bibliográficos
Autores principales: Johansen, Nelson, Quon, Gerald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693154/
https://www.ncbi.nlm.nih.gov/pubmed/31412909
http://dx.doi.org/10.1186/s13059-019-1766-4