Mutation-Derived Neoantigens for Cancer Immunotherapy

Mutation-derived neoantigens distinguish tumor from normal cells. T cells can sense the HLA-presented mutations, recognize tumor cells as non-self and destroy them. Therapeutically, immunotherapy antibodies can increase the virulence of the immune system by increasing T-cell cytotoxicity targeted to...

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Detalles Bibliográficos
Autores principales: Castle, John C., Uduman, Mohamed, Pabla, Simarjot, Stein, Robert B., Buell, Jennifer S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693295/
https://www.ncbi.nlm.nih.gov/pubmed/31440245
http://dx.doi.org/10.3389/fimmu.2019.01856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693295/
https://www.ncbi.nlm.nih.gov/pubmed/31440245
http://dx.doi.org/10.3389/fimmu.2019.01856

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