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Identification of optimal fluorescent probes for G-quadruplex nucleic acids through systematic exploration of mono- and distyryl dye libraries

A library of 52 distyryl and 9 mono-styryl cationic dyes was synthesized and investigated with respect to their optical properties, propensity to aggregation in aqueous medium, and capacity to serve as fluorescence “light-up” probes for G-quadruplex (G4) DNA and RNA structures. Among the 61 compound...

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Detalles Bibliográficos
Autores principales: Xie, Xiao, Zuffo, Michela, Teulade-Fichou, Marie-Paule, Granzhan, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693400/
https://www.ncbi.nlm.nih.gov/pubmed/31467609
http://dx.doi.org/10.3762/bjoc.15.183