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Nanoporous smartPearls for dermal application – Identification of optimal silica types and a scalable production process as prerequisites for marketed products

smartPearls are a dermal delivery system for poorly soluble active agents, consisting of nanoporous silica particles loaded with a long-term stable, amorphous active agent in its mesopores (2–50 nm). The amorphous state of the active agent is known to increase dermal bioavailability. For use in mark...

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Detalles Bibliográficos
Autores principales: Hespeler, David, El Nomeiri, Sanaa, Kaltenbach, Jonas, Müller, Rainer H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693413/
https://www.ncbi.nlm.nih.gov/pubmed/31467828
http://dx.doi.org/10.3762/bjnano.10.162