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Nanoporous smartPearls for dermal application – Identification of optimal silica types and a scalable production process as prerequisites for marketed products
smartPearls are a dermal delivery system for poorly soluble active agents, consisting of nanoporous silica particles loaded with a long-term stable, amorphous active agent in its mesopores (2–50 nm). The amorphous state of the active agent is known to increase dermal bioavailability. For use in mark...
Autores principales: | Hespeler, David, El Nomeiri, Sanaa, Kaltenbach, Jonas, Müller, Rainer H |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Beilstein-Institut
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693413/ https://www.ncbi.nlm.nih.gov/pubmed/31467828 http://dx.doi.org/10.3762/bjnano.10.162 |
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