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SIGMAR1/Sigma-1 receptor ablation impairs autophagosome clearance

Autophagosome-lysosome fusion is a common critical step in various forms of macroautophagy/autophagy including mitophagy, the selective degradation of mitochondria. Regulations of this fusion process remain poorly defined. Here we have determined the role of SIGMAR1, a unique endoplasmic reticulum m...

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Detalles Bibliográficos
Autores principales: Yang, Huan, Shen, Hongtao, Li, Jing, Guo, Lian-Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693456/
https://www.ncbi.nlm.nih.gov/pubmed/30871407
http://dx.doi.org/10.1080/15548627.2019.1586248