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SIGMAR1/Sigma-1 receptor ablation impairs autophagosome clearance
Autophagosome-lysosome fusion is a common critical step in various forms of macroautophagy/autophagy including mitophagy, the selective degradation of mitochondria. Regulations of this fusion process remain poorly defined. Here we have determined the role of SIGMAR1, a unique endoplasmic reticulum m...
Autores principales: | Yang, Huan, Shen, Hongtao, Li, Jing, Guo, Lian-Wang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693456/ https://www.ncbi.nlm.nih.gov/pubmed/30871407 http://dx.doi.org/10.1080/15548627.2019.1586248 |
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